課程資訊
課程名稱
專題討論
Seminar 
開課學期
105-1 
授課對象
生化科技研究所  
授課教師
楊健志 
課號
BST7000 
課程識別碼
B22 M0020 
班次
02 
學分
全/半年
半年 
必/選修
必修 
上課時間
星期四8,9(15:30~17:20) 
上課地點
農化二B10-1 
備註
必修4學期。
限碩士班以上
總人數上限:42人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1051BST7000_02 
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課程概述

專題討論。 

課程目標
專題討論。 
課程要求
待補 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
待補 
參考書目
待補 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第2週
9/22  評分標準說明 
第3週
9/29  劉沅瓚
Bailey, M., et al. (2016). "Stability of small ubiquitin-like modifier (SUMO) proteases OVERLY TOLERANT TO SALT1 and -2 modulates salicylic acid signalling and SUMO1/2 conjugation in Arabidopsis thaliana." J Exp Bot 67(1): 353-363. 
第4週
10/06  卞毓嘉
Lacroixa, M., et al. (2016). “E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity. ” PNAS
 
第4週
10/6  馬蓁華
Kabe Y, Nakane T, Koike I, Yamamoto T, Sugiura Y, Harada E, Sugase K, Shimamura T, Ohmura M, Muraoka K, Yamamoto A, Uchida T, Iwata S, Yamaguchi Y, Krayukhina E, Noda M, Handa H, Ishimori K, Uchiyama S, Kobayashi T, Suematsu M. 2016. Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance. Nat Commun 7.11030
 
第5週
10/13  王栩沅
eIF4A inactivates TORC1 in response to amino acid starvation. Foivos-Filippos Tsokanos et al., EMBO J, 2016

 
第5週
10/13  張育瑄
Thienpont B, Steinbacher J, Zhao H, D'Anna F, Kuchnio A, Ploumakis A, Ghesquiere B, Van Dyck L, Boeckx B, Schoonjans L, Hermans E, Amant F, Kristensen VN, Koh KP, Mazzone M, Coleman ML, Carell T, Carmeliet P, Lambrechts D. 2016. Tumour hypoxia causes DNA hypermethylation by reducing TET activity. Nature 537(7618):63-68. 
第6週
10/20  林珆安
Yuan Chen, Ting Zou, and Sheila McCormick. 2016. S-Adenosylmethionine Synthetase 3 Is Important for Pollen Tube Growth. Plant Physiology, September 2016, Vol. 172, pp. 244–253
 
第6週
10/20  黃柏翰
Charlie Hobbs, Harry A. A Dailey, Mark Shepherd. 2016. The HemQ coprohaem decarboxylase generates reactive oxygen species: implications for the evolution of classical haem biosynthesis. Biochemical Journal (2016) DOI: 10.1042/BCJ20160696  
第7週
10/27  林芷萱
Li, S., et al. (2016). "Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin." Proceedings of the National Academy of Sciences 113(35): E5108-E5116.

王乙喧
Kishore K Joshi, Tarmie L Matlack, Christopher Rongo. 2016. Dopamine signaling promotes the xenobiotic stress response and protein homeostasis. The EMBO JOURNAL 35, 1885-1901.

 
第8週
11/03  張孟亭
Amanpreet Kaur, et al. 2016. sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance. Nature 532, 250-254.

游適駿
Lingang Zhang, Hideki Kondo, Hironari Kamikubo, Mikio Kataoka, and Wataru Sakamoto. 2016. VIPP1 Has a Disordered C-Terminal Tail Necessary for Protecting Photosynthetic Membranes against Stress. Plant Physiology 171, 1983-1995 
第9週
11/10  張永群
James Jenkins, Dmitri B. Papkovsky, Ruslan I. Dmitriev. 2016. The Ca2+ /Mn2+ -transporting SPCA2 pump is regulated by oxygen and cell density in colon cancer cells. Biochem. J. (2016) 473, 2507–2518.

鍾建弘
Crickard JB, Fu J, & Reese JC (2016) Biochemical Analysis of Yeast Suppressor of Ty 4/5 (Spt4/5) Reveals the Importance of Nucleic Acid Interactions in the Prevention of RNA Polymerase II Arrest. Journal of Biological Chemistry 291(19):9853-9870.
 
第10週
11/17  高子萱
Dyson, B. C., et al. (2016). "FUM2, a Cytosolic Fumarase, Is Essential for Acclimation to Low Temperature in Arabidopsis thaliana." Plant Physiol 172(1): 118-127.


林彥霐
Jing L, Ka-Cheuk L, Nadja S, Christos K, Jeremie C, Agneta H, Linn R, Philippe B, Claes-Goran O, Kerstin B, Olov A. 2016. IGFBP1 increases b-cell regeneration by promoting a- tob-cell transdifferentiation. The EMBO Journal e201592903.
 
第11週
11/24  吳佳霖
Chakrabortee, S., et al. (2016). Luminidependens (LD) is an Arabidopsis protein with prion behavior. Proceedings of the National Academy of Sciences 113(21): 6065-6070.

李孟億
Daniela F. Quail, Robert L. Bowman, Leila Akkari, Marsha L. Quick, Alberto J. Schuhmacher, Jason T. Huse, Eric C. Holland, James C. Sutton, Johanna A. Joyce.2016.The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas.VOL 352 ISSUE 6288 sciencemag.org SCIENCE 
第12週
12/01  邱俊瑜
Siv Vingill, David Brockelt, Camille Lancelin, Lars Tatenhorst, Guergana Dontcheva, Christian Preisinger, Nicola Schwedhelm-Domeyer1 , Sabitha Joseph1,2,6 , Miso Mitkovski, Sandra Goebbels, Klaus-Armin Nave, Jorg B Schulz, Till Marquardt, Paul Lingor& Judith Stegmuller. (2016). "Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism‐like phenotype in mice." The EMBO Journal.

譚安絜
The 3.8 A resolution cryo-EM structure of Zika virus
Devika Sirohi1,*, Zhenguo Chen1,*, Lei Sun1, Thomas Klose1, Theodore C. Pierson2, Michael G. Rossmann1,†, Richard J. Kuhn1,† 
第13週
12/08  林煜晟
Serebryany, E., et al. (2016). "An Internal Disulfide Locks a Misfolded Aggregation-prone Intermediate in Cataract-linked Mutants of Human γD-Crystallin." Journal of Biological Chemistry 291(36):19172–19183.

張婷宇
Maciejewski A, Ostapchenko VG, Beraldo FH, Prado VF, Prado MA, Choy WY. 2016 Jul. Domains of STIP1 responsible for regulating PrPC-dependent amyloid-β oligomer toxicity. Biochemical Journal 473, 2119–2130. 
第14週
12/15  張智婷
Reitaro Tokumasu, Kosuke Yamaga, Yuji Yamazaki, Hiroyuki Murota, Koya Suzuki, Atsushi Tamuraa, Kana Bando, Yasuhide Furuta, Ichiro Katayam, and Sachiko Tsukita. 2016. Dose-dependent role of claudin-1 in vivo in orchestrating features of atopic dermatitis. Proceedings of the National Academy of Sciences of the United States of America 113, 4061-4068.

邱宇恩
Rebecca S. Levin, Nicholas T. Hertz, Alma L. Burlingame, Kevan M. Shokata, and Shaeri Mukherjee 2016. Innate immunity kinase TAK1 phosphorylates Rab1 on a hotspot for posttranslational modifications by host and pathogen. Proceedings of the National Academy of Sciences 113, 4776–4783. 
第15週
12/22  蘇俊融
Paul, M. V., et al. (2016). "Oxygen Sensing via the Ethylene Response Transcription Factor RAP2.12 Affects Plant Metabolism and Performance under Both Normoxia and Hypoxia." Plant Physiology 172(1): 141-153.